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Roche Pharma Research and Early Development (pRED)

From Alzheimer’s disease to antimicrobial resistance, our Research and Development (R&D) focuses on high-burden diseases to address unmet needs and improve patient outcomes.

Our scientists are amongst the best in the industry, discovering and translating cutting-edge science in the pursuit of delivering life-changing benefits to patients.

We continue to be driven by our long-term aim to deliver these medical advances that provide greater benefits to patients, and at the same time, reduce the healthcare burden on society.

pRED's research spans across 7 disease areas:

Cardiovascular & Metabolism,Immunology,Infectious diseasesand Ophthalmology,Neuroscienceand Rare diseases,and Oncology and Haematology

Discover our latest peer-reviewed scientific publications

Discover peer-reviewed publications you can cite, build on, or bookmark. Use filters to find what you need fast, across Clinical Development, Data & Analytics, Immunology, Infectious Diseases, Ophthalmology, Neuroscience & Rare Diseases, Oncology, Pharmaceutical Sciences, Therapeutic Modalities, Translational Bioengineering, and more.

Excellence in science: Breakthrough stories

See all stories

Patients can’t wait. From our novel classes of antibiotics to our next-generation discovery center in Basel, discover how Roche Pharma Research and Early Development turns science into breakthrough medicines. These articles take a closer look at the science, teams, and platforms that are driving the field for patients and society.

Meet some of the people behind our breakthroughs:

At pRED, it’s not the easy questions that excite us, it’s the biggest challenges in healthcare. That’s why we’ve set ourselves big goals to discover treatments that provide greater benefits for patients at a lower cost to society. This means having the expertise, resources and latest technologies at our fingertips, within an organisation that nurtures innovation built on curiosity and responsibility.

Photo of  Azad Bonni

Our scientists are moving away from simply working toward developing treatments to taking a more holistic approach across diagnostics and pharmaceuticals, so that we may one day chart a new course in Alzheimer’s management, having an impact on the lives of so many throughout the patient journey.

Azad Bonni

SVP and Global Head of Neuroscience & Rare Diseases at Roche Pharma Research & Early Development (pRED).

Photo of Hans Clevers

I have seen many research buildings and institutes in my life but nothing compares to the new pRED Center. When I entered the spaces in this building, I could feel my hands start itching - I wanted to be at the bench and starting an experiment. I know that this facility will foster innovation and inspire all of the scientists who come to work here.

Hans Clevers

Former Head of Pharma Research and Early Development at Roche and current ad interim Director of Roche's Institute of Human Biology

Photo of Niels Janssen

The Brainshuttleᵀᴹ technology has created enormous momentum in the industry. We’ve flipped the conversation from if it works to how well it works.

Niels Janssen

Senior Principal Scientist, Translational Pharmacokinetics, Pharmaceutical Sciences, Roche Pharma Research and Early Development (pRED)

Photo of Ken Bradley

I am very proud to work for Roche because we have this commitment to antibiotics and global health security. You see our people's commitment level and the passion they bring. They raised their hands to be part of this important effort to help save lives around the world.

Ken Bradley

Head of Infectious Diseases Discovery, Roche Pharma Research and Early Development (pRED)

Photo of Roberto Villaseñor Solorio

Changing intrathecal injection to peripheral administration [e.g. intravenous or subcutaneous injection] would mean reducing the treatment burden for patients and could revolutionise their care journey.

Roberto Villaseñor Solorio

Principal Scientist, Neuroscience and Rare Diseases, Roche Pharma Research and Early Development (pRED)

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Innovation

Partnering

At Roche Partnering, we are passionate about science: yours and ours. Through partnerships, we hope that together we can build a better future with medicines that make a real difference to patients.

Innovation

Roche R&D locations

We have research and development sites all around the world.

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Institute of Human Biology

The Institute of Human Biology (IHB) is dedicated to research on human biology and human model systems such as organoids. Roche Pharmaceutical Research and Early Development (pRED) established the IHB to take maximum advantage of the scientific and research expertise in both academia and the pharmaceutical industry, it will bring them closer together using human model systems to better predict a drug’s validity, and so translate pioneering science into breakthroughs for patients.

Innovation

Roche Accelerator

As Roche’s first in-house accelerator globally, Roche Accelerator aims to serve as an external innovation hub, to catalyze next-generation R&D and contribute to the innovation ecosystem.

[Thumbnail] RocheAccelerator
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RNA Hub

An integrated multidisciplinary RNA research community with focus on oligonucleotides And access to all of Roche’s research capabilities

Joint postdoctoral programme with ETH Zurich

To advance the development and application of bioengineering in translational medicine, the ETH Zurich Department of Biosystems Science and Engineering and Roche Pharma Research and Early Development launched the Bio-​Engineering Systems for Therapeutics (BEST) postdoc programme in Basel.

Students in a lab wear white coats and safety goggles. One uses a pipette with a focused expression. The bright room has a collaborative atmosphere.