Investor Update

Basel, 08 February 2017

New E-Mail Address for Roche Investor Updates

Dear Investor,

This is to inform you that, as of 13 February 2017, Roche will send its Investor Updates from a new e-mail account with a new layout. Please make sure the new e-mail address is added to your ‘safe sender’ list. The new e-mail address is:

Do not hesitate to contact us if you have any questions.

With best regards,

Roche Investor Relations