What’s it worth? The value of innovation in APAC
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Disease has a profound impact on people's lives, affecting their health, independence and quality of life. Its effects also extend beyond the individual, increasing pressures on families and caregivers and placing growing demands on healthcare systems and economies.
The scale of that burden is why health should be treated as an investment in APAC's future.
Global evidence shows that every USD 1 allocated to healthcare can generate up to USD 4 in economic benefit.1
The urgency is clear
Non-communicable diseases (NCDs) account for nearly 75% of all deaths worldwide. The heaviest burden falls on low- and middle-income countries (LMICs) where 86% of premature NCD deaths occur.2
APAC is disproportionately affected. NCDs account for nearly 90% of deaths in the WHO Western Pacific region and 55% in South-East Asia region, a burden compounded by rapid ageing.3-5
As this demographic shift accelerates, demand for healthcare will continue to rise.
It impacts society as a whole
Poor health doesn’t stop with the individual. When people are unwell, earning capacity declines, productivity falls, and society bears the knock-on effects. In APAC, 9–12% of national GDP could be lost to ill health in the workforce.6
With roughly 1 in 3 working age adults in Asia living with multiple long-term conditions, protecting working-age health is critical to strengthening individual, economic, and social resilience, and to unlocking the region’s long-term potential.7,8
Breast cancer shows the scale of impact a disease can have on patients, society and the economy. Asia accounts for ~45% of new global cases and ~48% of deaths, many in prime working years.9,10 HER2+ breast cancer is expected to drive ~USD 116 billion in productivity losses across 11 APAC economies (2017 - 2027).11
In many APAC societies, people remain in the workforce for longer and older family members play an important caregiving role. Illnesses can reduce independence and limit their ability to contribute, shifting pressure back onto working-age individuals.5
Protecting healthy ageing is critical to sustain intergenerational support in APAC.
In APAC, 46% of individuals expressed concern that vision loss would affect their ability to keep a job or earn an income.12 Combined, age-related macular degeneration (AMD) and diabetic macular edema (DME) are expected to drive USD 64 billion in productivity loss across 11 APAC economies by 2027.11 Preserving sight protects more than quality of life, it protects people's ability to stay economically independent as the region ages.
So, what's it worth?
Innovation is how we bend the curve.
In APAC, that value is already taking shape.
1. Meeting rising health demand
A global study found that 73% of the increase in mean age at death across 26 countries between 2006 and 2016 was driven by pharmaceutical innovation.13 By 2040, investment in health and innovation could save 60 million lives and add $12 trillion to the global economy while reducing hospitalisations to support more sustainable healthcare systems.1
For APAC, a region facing rising demand and rapid ageing, this points to what earlier innovation and investment could deliver.
2. Strengthening socioeconomic development
Improvements in population health have driven up to one-third of economic growth in developed economies over the past century.1 Returns are even stronger in LMICs, where every USD 1 invested in NCD prevention and control could return up to USD 7 within a decade, contributing to an estimated USD 230 billion by 2030.14
Roche medicines contribute significant health and economic value. In HER2+ breast cancer, treatments could return ~USD 1.65 billion in economic value and deliver ~21,300 QALYs between 2017 and 2027. In vision care, treatments could return ~USD 168 million in economic value and deliver ~1,441 QALYs from 2022-2027. 11
3. Supporting the region’s long-term strategic growth
Beyond delivering socioeconomic value through improving healthy life years, biopharma innovation brings wider economic returns through capital inflows, high-value jobs, and stronger innovation capability.
Globally, the pharmaceutical industry contributes around USD 2.3 trillion to GDP and supports nearly 75 million jobs, reflecting its role not only as a health enabler but as a major driver of economic growth and high-value employment.15 That value becomes real-world gains for people, society, and the economy, across APAC.
Evidence shows that strengthening health system efficiency and capacity, alongside sustained investment, can deliver improved health outcomes while driving productivity and economic growth.16
Investing in health innovation is an investment in the strength and growth of society itself.
Globally, every USD 1 of direct output from the pharmaceutical industry generates an additional USD 2.04 across the wider economy.15
We must act now
Over 12,700 new medicines are in development globally, with at least one APAC site included in 55% of global clinical trials.17,18 APAC is well-positioned to unlock the full value of health innovation for better health, economy, and society.
References
Remes, J., Linzer, K., Singhal, S., Dewhurst, M., Dash, P., Woetzel, L., Smit, S., Evers, M., Wilson, M., Rutter, K., & Ramdorai, A. (2020, July 8). Prioritizing health: A prescription for prosperity. McKinsey Global Institute. Retrieved July 23, 2026, from https://www.mckinsey.com/industries/healthcare/our-insights/prioritizing-health-a-prescription-for-prosperity
World Health Organization. (2025). Noncommunicable diseases. Retrieved July 23, 2026, from https://www.who.int/health-topics/noncommunicable-diseases#tab=tab_1
World Health Organization Regional Office for the Western Pacific. (2023). Health statistics in the Western Pacific Region 2023: Monitoring health for the Sustainable Development Goals. ReliefWeb. Retrieved July 23, 2026, from https://reliefweb.int/report/australia/health-statistics-western-pacific-region-2023-monitoring-health-sdgs
World Health Organization Regional Office for South-East Asia. (n.d.). Noncommunicable diseases. Retrieved July 23, 2026, from https://www.who.int/southeastasia/health-topics/noncommunicable-diseases
United Nations, Economic and Social Commission for Asia and the Pacific. (2022). Asia-Pacific report on population ageing 2022: Trends, policies and good practices regarding older persons and population ageing. Retrieved July 23, 2026, from https://www.unescap.org/sites/default/d8files/knowledge-products/AP-Ageing-2022-report.pdf
Marsh & McLennan Companies. (2017). Aging workforce: cost and productivity challenges of ill health in Singapore. Retrieved July 23, 2026, from https://www.marsh.com/content/dam/marsh/Documents/PDF/asia/en_asia/Aging_Workforce_Cost_and_Productivity_Challenges_of_Ill_Health_in_Singapore.pdf
Chowdhury, S. R., Das, D. C., Sunna, T. C., Beyene, J., & Hossain, A. (2023). Global and regional prevalence of multimorbidity in the adult population in community settings: A systematic review and meta-analysis. EClinicalMedicine, 57, 101860. Retrieved July 23, 2026, from https://linkinghub.elsevier.com/retrieve/pii/S2589537023000378
Seong, J., Bradley, C., Leung, N., Woetzel, J., Ellingrud, K., Kumra, G., & Wang, P. (2023, September 22). Asia on the cusp of a new era. McKinsey Global Institute. Retrieved July 23, 2026, from https://www.mckinsey.com/mgi/our-research/asia-on-the-cusp-of-a-new-era
International Agency for Research on Cancer. (2024). Breast cancer fact sheet (GLOBOCAN 2022). World Health Organization. Retrieved July 23, 2026, from https://gco.iarc.who.int/media/globocan/factsheets/cancers/20-breast-fact-sheet.pdf
Wang, F., Liu, S., Li, J., Shi, Y., Geng, Z., Ji, Y., & Zheng, J. (2025). Burdens of breast cancer and projections for 2030 among women in Asia: Findings from the 2021 Global Burden of Disease Study. Current Oncology, 32(5), 267.Retrieved July 23, 2026, from https://doi.org/10.3390/curroncol32050267
Maghularia, R., Atitallah, A., Levi, E., Müller, M., Liaqat, H., Lovera, D., Caragata, L., Fazli, M., Needham, M., Lester, O., & Hape, A. (2026). Value of investing in innovative medicines: socioeconomic burden and annual social impact of Roche treatments for HER2+ breast cancer and retinal diseases in APAC. WifOR Institute. Retrieved July 23, 2026, from https://www.wifor.com/en/download/value-of-investing-in-innovative-medicines-socioeconomic-burden-and-annual-social-impact-of-roche-treatments-for-her2-breast-cancer-and-retinal-diseases-in-apac/?wpdmdl=364217&refresh=6a4ce9ea966f21783425514
Roche. (2025). Insights Report: Vision Care in APAC – Understanding the Societal and Economic Burden. Retrieved July 23, 2026, from https://cloud.email-epicx.roche.com/Roche-APAC-Vision-Health-Survey
Lichtenberg, F. R. (2022). The effect of pharmaceutical innovation on longevity: Evidence from the U.S. and 26 high-income countries. Economics and Human Biology 46(2022).
World Health Organization. (2021). Saving lives, spending less: the case for investing in noncommunicable diseases. Retrieved July 23, 2026, from https://iris.who.int/server/api/core/bitstreams/ac85a63e-2a16-4eec-8ae8-147b9c686f8c/content
Junieja, M., Mai, L., & Albu, N. (2024). The economic impact of the global pharmaceutical industry. International Federation of Pharmaceutical Manufacturers & Associations (IFPMA). Retrieved July 23, 2026, from https://www.ifpma.org/publications/the-economic-impact-of-the-global-pharmaceutical-industry/
World Bank. (2025, April 17). Health, economic growth and jobs. Retrieved July 23, 2026, from https://www.worldbank.org/en/topic/health/brief/health-economic-growth-and-jobs
D. Reddy. (2024, December 9). Delivering the next generation of medicines and vaccines for a healthier future. International Federation of Pharmaceutical Manufacturers & Associations (IFPMA). Retrieved July 23, 2026, from https://www.ifpma.org/insights/delivering-the-next-generation-of-medicines-and-vaccines-for-a-healthier-future/
Siu, A., & Gupta, S. (2024). Exploring the Asia-Pacific Clinical Trials Landscape. Asking the 5 W’s. Citeline. Retrieved July 23, 2026, from https://www.citeline.com/-/media/citeline/resources/2024/10/exploring-the-asia-pacific-clinical-trials-landscape/white-paper_clinical-trials-roundup-apac-deep-dive.pdf
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