Published 07 April 2020, updated 14 April 2020
While many stay home to curb the spread of the new coronavirus, Roche sites continue to operate around the clock. Tirelessly and tenaciously, manufacturing and packaging teams continue to produce and ship medicines and tests that people need urgently.
Long before the world learned about the global health threat of COVID-19, the everyday heroes behind the scenes at Roche knew the gravity of their mission. Cancer patients depend on them for treatments. Those with autoimmune diseases, heart disease and other rare diseases do, too.
Clinical development and ongoing trials cannot just stop. Neither can cells in the labs, which don’t sleep. Diagnostic tests are steadily needed and must be shipped all across the globe... Around the world, healthcare communities and patients depend on deliveries of Roche solutions − every day, and now more than ever.
So they leave their families and work long shifts, day after day. Leaders from engineering volunteer overnight in warehouses to keep things moving 24/7. Some employees live onsite because border crossings are uncertain or delayed if they go home. These are the everyday heroes behind the scenes at Roche.
Feeling the weight of the world, they are dedicated to keeping the facility running at full speed.
At first glance, the Penzberg plant appears abandoned. But in some parts of the buildings, there is a hustle and bustle, with employees working at incredible speed. The facilities at Diagnostics Operations Penzberg (DOZ) are running at full capacity. The division produces ingredients and reagents that help in the fight against COVID-19. Markus works as a laboratory chemist in the production at DOZ in Penzberg and is dedicated to keeping things running smoothly.
"Patients all over the world depend on our products. Many of the critical materials that help in detecting novel coronavirus come out of Penzberg, explains Markus. “With our work we help to ensure that patients and entire societies can properly evaluate and take measures to stop the spread,” he says.
As countries around the globe are struggling with supplies that assist in fighting and detecting the virus, the immense pressure to produce while also keeping the team healthy is not lost on Markus. "Demand is constantly increasing. In order to meet the needs, we produce 24 hours a day, seven days a week. We also depend on some external factors. At the moment we are trying to obtain all the necessary raw materials in sufficient quantities. We also have to coordinate the following filling process in such a way that our colleagues can manage it,” he says.
Because the team is highly trained, they have also taken precautionary measures to ensure that not even the coronavirus itself will stop them producing these desperately needed supplies. Markus explains that “in order to protect ourselves and stay safe, we have separated colleagues working on our floor into different groups. Those groups are not allowed to physically meet. Other colleagues are working from home and we communicate via Hangouts." It’s unchartered territory for the team, but there’s no shortage of motivation and passion to continue their mission.
Like a finely made timepiece, the process chain works hand-in-hand to speed drugs through the plant to patients in need.
"Working from home so much feels a little strange for me," says Niels Bauer, a straight-talking foreman in Pharma Operations Packaging in Mannheim. "Usually, I'm always in the middle of things."
But these times require us all to adapt and do things differently. His schedule today? Coordination tasks, and that can be done from home.
"Anyone who isn't working directly in production has no business on site," Niels says with a smile.
But the pandemic has its own plans for people working in Pharma Operations. One drug that Niels and his colleagues pack in Mannheim is in a global clinical trial. Demand for the medicine grows rapidly in other countries, such as Italy. The team recently prepared 20,000 vials for Italy in less than a day.
“‘The packaging arrived. The truck is coming tomorrow. When can you start?’ they asked,” Niels says. “Then the whole chain simply has to work perfectly in order to bring the product on the truck on time."
Everyone in the team knows that if a product is missing, people could die. At the same time, other products must continue to flow. So Pharma Operations ramped up production.
"We all move in the same direction, pass the ball flexibly while running, and the solutions are pragmatic – despite the much larger order volume," Niels says.
“The dynamics are demanding, but this makes us a great team. The patient may be rather far away from us, but the thought that a drug would become scarce and thus endanger patient care is a great motivation – every day anew."
A small team of Roche scientists helped ease the hand sanitiser shortage with ingenuity and care.
A clean work environment is important for a large campus with thousands of employees to prevent the spread of germs such as COVID-19. And in some parts of Roche, such as labs and manufacturing areas, hand sanitiser is critical to maintaining a sterile, germ-free environment to conduct experiments and produce medicines for patients around the world.
As reports of hand sanitiser shortages spread across the globe, teams at Roche didn’t panic. They rolled up their sleeves, took initiative and demonstrated teamwork and agility in action.
To help ensure a healthy environment for those who continue to work on site at Roche headquarters in and around Basel, Switzerland – and assist the greater community by reducing the spread of germs while still making medicines – the Global Technical Development (PTD) Synthetic Molecules scientists and Basel safety, security, health and environmental (SHE) group teamed up to make “homemade” disinfectant.
“The team is thinking of the community, acting with urgency and prioritising work so quickly while continuing to deliver on their primary mission of Doing now what patients need next,” says Dharmendra SinghalI, Head Technical Development, Small Molecules at Roche. “They are helping keep business-critical employees safe on site so we can continue to serve our patients.”
The group manufactured 1000 liters of disinfectant in one day and distributed it to the Basel and Kaiseraugst sites. To meet demand, the team ramped up to 4000 liters a week in an effort to make enough for its employees who continue to work round-the-clock to help patients with medicines and testing solutions.
“Keep on sanitising your hands!” says Dharmendra. “I can’t think of a better example of changing a manufacturing schedule on such short notice to quickly fit this in – it’s an example of working together and making it happen.”