Non-Hodgkin lymphoma (NHL) is a type of blood cancer that starts in the white blood cells, known as lymphocytes, which are a key component of the immune system.¹ There are over 60 different types of NHL,² which can also be classified as indolent (slow growing) or aggressive (fast growing), depending on how quickly the cancer grows.³ Two of the most common types, follicular lymphoma and diffuse large B-cell lymphoma (DLBCL), are very different in how, when and where they develop and how they are managed.
Swerdlow SH, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. In: World Health Organization Classification of Tumours. Lyon, France: IARC; 2017.
Rovira J et al. Prognosis of patients with diffuse large B cell lymphoma not reaching complete response or relapsing after frontline chemotherapy or immunochemotherapy. Ann Hematol. 2015; 94: 803–812.
Maurer, MJ et al. Event-free survival at 24 months is a robust end point for disease-related outcome in diffuse large B-cell lymphoma treated with immunochemotherapy. J Clin Oncol. 2014; 32: 1066-73.
Maurer MJ, Habermann TM, Shi Q, et al. Progression-free survival at 24 months (PFS24) and subsequent outcome for patients with diffuse large B-cell lymphoma (DLBCL) enrolled on randomized clinical trials. Ann Oncol. 2018;29:1822-1827.
Fowler N. Role of Maintenance Rituximab (Rituxan) Therapy In the Treatment of Follicular Lymphoma. Pharmacy and Therapeutics; 2011; 36:590-598