Zelboraf (vemurafenib)
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Zelboraf is an oral, small molecule kinase inhibitor indicated for the treatment of patients with BRAF V600 mutation-positive advanced or inoperable melanoma. It is designed to inhibit some mutated forms of BRAF, which cause abnormal signaling inside cancer cells leading to tumor growth.

Zelboraf is approved in more than 90 countries, including the US, Switzerland and the EU, and has been used to treat more than 60,000 patients worldwide. Zelboraf was co-developed under a 2006 license and collaboration agreement between Roche and Plexxikon, now a member of the Daiichi Sankyo Group.