Pharmacokinetics studies how organisms deal with a drug substance depending on its route of administration. It delivers information on the behavior and absorption of the drug through the digestive system (in case of oral administration), the rate and geography of its distribution via the blood to the various organs and the way the body gets rid of it by breakdown and elimination. The short-hand term ADME (Absorption, Distribution, Metabolism and Elimination) is often used to indicate the sum of these phenomena. Bio-analytical methods, able to detect minute amounts of the drug and its metabolites in body fluids, are a fundamental tool of pharmacokinetic studies, as well as refined drug imaging technologies using a radiolabeled or otherwise tagged version of the drug substance.

Tags: Translational Technologies