In Silico PK/PD Modeling
In Silico Modeling is deployed to predict how the pharmacology and pharmacokinetics of the drug as seen in laboratory and animals studies might translate to humans. Complex computer simulations of human and animal physiology are used to foresee how a drug substance will behave when dosed to humans, before any human data exist. In silico models of diseases are also developed to explore their cause and underlying mechanisms or how patients' symptoms will progress over time with or without new treatments. These technologies are used to identify potential drug targets, predict the relation between dose, drug concentration in the body and effectiveness of the treatment, identify suitable patient populations or markers of drug effects, optimise the design of clinical studies and analyse data from clinical rials, on the desired outcome.