Teratogenicity Screening


Teratogenicity Screening is a part of the panel of Reproductive Toxicology studies that look at potential adverse effects of a drug on fertility as well as the development of the embryo if the mother is exposed to the drug during pregnancy. In the research phase, we look mainly at the effect of potential drug substances on embryonic stem cells, which are a relevant model for the first steps of embryonic development. The so-called EST (Embryonic Stem Cell Test) assay looks at the effect of drug candidates on the well-being of the cells and their capacity for differentiation. It can give early indication of potential teratogenic issues and risks for the developing embryo.

Tags: Drug Safety