Carcinogenicity Screening


Carcinogenicity Screening is a very important element to guarantee the safety of potential drugs. Carcinogenic effect can be easily missed in clinical studies, as it can take years of dosing and a high number of treated patients to see such an effect. Potential carcinogens, however, can be identified very early in in vitro assays that look at the potential of substances to cause genetic damage – one of the main sources of carcinogenicity. As there are different types of mechanisms for genetic damage, carcinogenicity testing is performed with a battery of different tests, part of which has been automated to allow testing in the early phases of drug discovery.

Tags: Drug Safety