Antibodies, like many other natural proteins, are normally decorated with sugars. Optimizing the pattern of sugars associated with synthetic antibodies can have an enormous impact on their therapeutic efficacy. This technology, known as glycoengineering, is the focus of the Roche research centre in Schlieren, Switzerland.
Drawn to Science cheat sheet for Glycosylation of antibodies
In tests, 100 percent of the sugar chains were correctly completed by our galactosyl transferase.
The glycoengineering technology is a technology that allows you to enhance the effect of an antibody so that it can recruit the immune system to better kill tumour cells…
Our cancer treatments are increasingly directed at the human immune system