We are pleased to invite investors and analysts to participate in a live audio webcast and conference call on Tuesday, 28 April 2020 , highlighting data from the Roche neuroscience portfolio that were accepted to be part of the American Academy Of Neurology 72^nd Annual Meeting 2020 and will be available virtually.

Agenda:

• Welcome
  Karl Mahler, Head of Investor Relations and Roche Group Planning
• Risdiplam: FIREFISH part 2 efficacy and safety in infants with type 1 SMA
  Prof. Laurent Servais, MDUK Oxford Neuromuscular Center, Department of Paediatrics, University of Oxford, UK
• Risdiplam: Update on clinical development program
• OCREVUS: Long-term data on key markers of disability progression in MS Shorter infusion (ENSEMBLE PLUS) data and regulatory update
  Paulo Fontoura, M.D. Ph.D., Global Head Neuroscience and Rare Diseases Clinical Development
• Q&A

Please dial in as outlined below:
17:30 – 18:30 CEST / 16:30 - 17:30 BST
11:30 – 12:30 am EDT / 8:30 - 9:30 am PDT

Audio webcast and conference call will start with a presentation, followed by a Q&A session (live access to the speakers).

Access to Audio webcast

Please access by clicking on ir.roche.com.

Access to Conference Call (pre-registration required)

You will receive phone numbers, passcode and your personal PIN to directly access the conference call by pre-registering here.

Should you have any issues with the registration, please dial the following numbers on the day of the conference call 10-15 minutes prior to conference start:

+41 (0) 58 310 50 00 (Europe & RoW)
+44 (0) 207 107 06 13 (UK)
+1 (1) 631 570 5613 (USA)
Other international numbers are available here

A replay of the webcast will be available via ir.roche.com.