We are pleased to invite investors and analysts to participate in a live audio webcast and conference call on Thursday, 2 August 2018, featuring data from the Phase 2 LADDER study of the Port Delivery System (RPDS) with Lucentis to be presented at the American Society of Retina Specialists (ASRS) annual meeting (20-25 July 2018) in Vancouver, Canada. We would like to invite all interested parties to dial in as outlined below: 16:00 - 17:00 CEST / 15:00 - 16:00 BST 10:00 am - 12:00 pm EDT / 7:00 am - 8:00 am PDT Audio webcast and conference call will start with presentations followed by a Q&A session (live access to the speakers). The live audio webcast can be accessed via ir.roche.com. In order to receive your personal dial-in details and expedite your access to the conference call, please pre-register under this link. If you have not pre-registered, please find the dial-in numbers below, we recommend you to dial in to the conference 10-15 min prior to the scheduled start. +41 (0) 58 310 5000 (Europe and ROW) +44 (0) 207 107 0613 (UK) +1 (1) 631 570 5613 (USA Toll Free) Presentation slides will be posted on the Roche IR website. A replay of the webcast will be available via ir.roche.com.

Best regards, Karl Mahler                                                      Loren Kalm Head of Investor Relations                              Investor Relations Officer

Roche Investor Relations
Dr. Karl Mahler Phone: +41 61 68-78503 e-mail: karl.mahler@roche.com	Dr. Sabine Borngräber Phone: +41 61 68-88027 e-mail: sabine.borngraeber@roche.com
Dr. Bruno Eschli Phone: +41 61 68-75284 e-mail: bruno.eschli@roche.com	Dr. Susann Manchado Phone: +41 61-68-75619 e-mail: susann.manchado@roche.com
Dr. Birgit Masjost Phone: +41 61 68-84814 e-mail: birgit.masjost@roche.com
Investor Relations North America
Loren Kalm Phone: +1 650 225 3217 e-mail: kalm.loren@gene.com

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