Investor Update

Basel, 21 June 2010

Reminder: Invitation to Roche investor science event: Phase III data on RG1583(taspoglutide) GLP-1 analogue and overall update on Roche's franchise in diabetes & metabolism

Reminder: Invitation to Roche investor science event:
Phase III data on RG1583(taspoglutide) GLP-1 analogue and overall update on Roche´s franchise in diabetes & metabolism
Monday, 28 June 2010, Orlando, USA

We kindly invite investors and analysts to participate in an event to present and discuss new phase III data and results on RG1583(taspoglutide) GLP-1 analogue presented during the 2010 ADA (American Diabetes Association) 70th Scientific Sessions. Further, Roche will provide an overall update on its franchise in diabetes and metabolism.

The Roche investor science event will take place on:

Monday, 28 June 2010 from 6:30 p.m. to 8:00 p.m. Eastern Standard Time (EST)

Rosen Shingle Creek Hotel
9939 Universal Boulevard
Orlando, FL 32819
Gaitlin A1 room

Following presentations and the Q&A session, Roche Investor Relations is inviting participants to stay for a dinner reception.

Please contact Tysha Wheeler at tysha.wheeler@roche.com before 23 June 2010 if you would like to attend this event or if you have any questions.

Conference call

Investors and analysts who cannot attend in person in Orlando are invited to join the accompanying conference call either by live audio webcast or by telephone:

Live audio webcast

The live conference call can be accessed via http://ir.roche.com. Following the event, an audio file will be made available for download.

Phone conference call

The live conference call can be accessed using the following dial-in numbers:

+41 91 610 5600 (Switzerland)
+44 207 107 0611 (UK)
+1 866 291 4166 (USA)

Please dial in to the conference call 10 – 15 minutes before the call is scheduled to start.

A replay of the conference call will be available one hour after the conference call and then for 48 hours. The replay can be accessed using the following dial-in numbers:
+41 91 612 4330 (Switzerland)
+44 207 108 6233 (UK)
+1 866 416 2558 (USA)

Enter the ID 17905 followed by the # sign

Slide presentation

At the time of the conference call, the accompanying presentation will be available from the IR website at http://ir.roche.com.