Principal Outcomes Research Scientist

United Kingdom, England, Welwyn Garden City, Hertfordshire

Roche are advertising a uniquely rare opportunity to join the Patient-Centered Outcomes Research team at either of our sites in; Welwyn Garden City (UK). This role will report directly into the Global Head of Patient-Centered Outcomes Research for Neuroscience.

When joining the Patient-Centered Outcomes Research (PCOR) team, the patient (and caregiver’s) voice will be central to everything that you do. You will ensure that the patient is at the very heart of product development and have the opportunity to develop novel innovative endpoints that inform probability of technical success in drug development as well as help facilitate market access.  The PCOR team provides strategic consultancy and scientific expertise to support clients in functions such as Clinical, Regulatory and Global Pricing and Market Access.  The PCOR team is proactively involved in several external initiatives continuously striving to shift the status quo with a focus on patient engagement, measurement and novel endpoint development intended to inform treatment benefit (e.g. CPATH, NIH, ISOQOL etc). The team is a global multidisciplinary group of Psychologists, Health Service Researchers, Epidemiologists, Clinical Scientists and statisticians.

In this role you will lead the development of global measurement strategies such as Patient-Reported Outcomes (PROs) and Clinician Reported Outcomes (ClinROs) for multiple molecules within a therapeutic area. You will be required to communicate and set direction for areas of responsibility, develop and maintain relationships with key stakeholders internally and externally, and to think out of the box and challenge the status quo.

Your substantial experience will mean that you will be well recognised in the field of outcomes research. Your role will be exciting and varied as you will be involved in a range of responsibilities. These include establishing and leading PCOR disease area strategies. You may make decisions on the disease area or a portion of the portfolio including, but not limited to, establishing humanistic impact of a condition and its treatment on patients and caregivers; reviewing, modifying or developing conceptual models and developing hierarchical endpoint models. You will be responsible for assessing whether instruments are Fit-for-Purpose with particular attention to content validity and psychometric properties specific to context of use. You will make strategic recommendations to address any gaps clearly distinguishing between ‘must have’ vs ‘nice to have’.

Using your excellent communication and negotiation skills, you will be responsible for managing vendors including work development, contract initiation, project milestones, timelines, deliverables, and budgets. Your ability to quickly establish and maintain professional relationships will enable you to act as PCOR functional lead in cross-functional teams to establish needs and develop PCOR strategies. You will also need to ensure, where appropriate, that PCOR activities translate into business deliverables such as target product profiles, lifecycle investment plan criteria, clinical development plans and probabilities of technical success.

Your strong leadership skills will enable you to successfully mentor Outcomes Research Scientists & Senior Outcomes Research Scientists and set direction for areas of responsibility. You may be called upon to participate on various leadership teams as required.

You will also regularly contributing to external efforts such as International Society of Quality of Life Research (ISOQOL), International Society of Pharmacoeconomics & Outcomes Research (ISPOR), CPATH, FDA initiatives, National Institute of Health (NIH) initiatives etc.