Postdoctoral fellow within Ocular Product Development, Pharma Technical Development
At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. We believe in the urgency of delivering medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision-making and taking action. And we believe that good business means a better world.
Pharma Technical Development Europe (PTDE) brings game-changing therapies from clinical phase I into the market to serve every patient, every day. Our core business is to develop safe, innovative and effective drugs using cutting-edge technologies for manufacturing processes (Drug Substance and Drug Product), clinical supply, formulation, device, packaging, drug delivery and analytical development.
As a postdoctoral fellow, you will be part of the Ocular & Drug Delivery Home within the Department “Pharmaceutical Development and Supplies” in Basel, Switzerland. You have an interest in developing tissue models for predicting drug stability and delivery, and are willing to work with both basic and applied researchers. Your major responsibilities in this specific position are the following:
Develop and validate innovative in vitro model systems that replicate the structural and physico-chemical features of human ocular tissues.
Apply new analytical approaches, bioengineering methods and analysis methodologies to provide robust, reliable and reproducible readouts
Implement the established models, in combination with automated solutions, into the evaluation of next-generation in-house drug technologies
Collaborate with a vibrant scientist community across several department at Roche, as well as with external academic partners
Generate high-quality results for peer-reviewed publications and patents, and present them at scientific meetings
You hold a PhD in pharmaceutical sciences, biochemistry, molecular biology, tissue engineering or a related field. Your experience and investigative attitude allow you to work independently, to design, perform, and interpret experiments, and to adopt new and abstract scientific methodologies.
The position would require advanced expertise in:
Biological tissues and biomaterials, preferably in the field of ophthalmology and extracellular matrices
State-of-the-art approaches in tissue engineering (e.g. tissue microfabrication, multilayer bioprinting etc.)
Experience in advanced microscopy and analytical techniques, such as dynamic light scattering, atomic force and fluorescence microscopy
Excellent team and collaboration skills
Excellent command of English (written and oral).
A one-year contract will be offered with the possibility of extension by an additional year.
Are you ready to apply? Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represent a range of backgrounds, perspectives, and skills.