As a Principal Mechanical Engineer within the Roche Systems Technology Group, you will play a key role in architecting, designing and developing new scientific and diagnostic instruments and their sub-systems. These instruments consist of fluidic, mechatronic, pneumatic, thermal, optical and electrical sub-systems and are responsible for automating workflows such as those involved in patient sample processing, nucleic acid extraction, library preparation and DNA sequencing.
Responsibilities include defining and interpreting requirements and specifications, creating system and sub-system architecture, selecting and evaluating components and designing custom components, mechanisms, modules and sub-assemblies. Other critical functions include sub-system and system level assembly, characterization, testing and troubleshooting, as well as analyzing data, writing reports and presenting results. You will work closely with other engineers and scientists on integration efforts and provide guidance and oversight to other team members, consultants, contractors and vendors
The ideal candidate shall exhibit a high degree of ingenuity and resourcefulness to help us solve problems, invent new technology and develop cutting-edge products.
A Bachelor’s degree in Mechanical Engineering, or equivalent experience and/or education, with a minimum of 5 years of relevant industry experience designing, building, and/or supporting life science instrumentation or diagnostic/medical devices. Candidates with exceptional aptitude and experience from other fields or disciplines will also be considered
Contributed to the design or development of at least two life science or diagnostic instruments or devices
Experience designing systems for handling samples and reagents used in the analysis, processing or production of RNA, DNA and/or proteins
Experience designing and implementing complex, high performance fluidic systems utilizing custom manifolds with integrated pumps, valves, sensors, temperature control elements and other components
Experience designing automation systems and related mechanisms using both electric and pneumatic actuators
Solid understanding of physics and engineering fundamentals
A positive, proactive attitude and a strong passion for science, engineering and high-impact product development
Excellent written and verbal communication skills
Demonstrated success working in multidisciplinary team environments
Expertise in CAD for mechanical design and FEA simulations (Solidworks highly preferred)
Proficiency with common machine shop tools as well as test and measurement equipment
Proficiency with rapid prototyping technology such as 3D printers, laser cutters, CNC mills/lathes
Proficiency with Python, LabVIEW or similar tools for device control and data acquisition
Proficiency with MATLAB and Python for analysis, modeling and simulations.
Proficiency with Solidworks PDM or similar document management tools
Experience with design control under ISO standards
Experience designing for high volume injection molding
Proficiency in GD&T
Understanding of chemistry, biological assays and sequencing technology