Roche Postdoctoral Fellow (RPF) in Ophthalmology Medical Genomics (2 years temp. contract/ Start: 01.02.2021)

Switzerland, Basel-City, Basel

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At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

That is why we come to work every single day. We commit ourselves to scientific detail, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow


The position 

As a Postdoctoral Fellow in the Ophthalmology Discovery Department at the Roche Innovation Center Basel, you will focus on exploratory research projects on developing efficient and specific tools for targeting ocular cells for therapy.  In this position you will:

  • Develop a screening platform to identify novel regulatory elements for cell-specific and physiologically-relevant molecule expression in ocular cells, using bioinformatics, molecular biology, biochemistry and cell biology methods

  • Optimize molecular tools for efficient gene transfer into ocular cells using in vitro and in vivo model systems 

This position is sponsored by the Roche Postdoctoral Fellowship Programme. 

The RPF Programme has the ambition to build and maintain the Scientific Leadership of the future and to provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers, and leading academic research groups, from around the world. One of the key aims is to advance basic science and technologies that will be published in top-rated, peer-reviewed scientific journals if necessary preceded by priority patent applications.

The duration of an RPF project is initially set for two years, with the possibility of extension for a third year. You will be based in Roche Innovation Center in Basel.

More information about the RPF Programme:


Who you are:

  • You are a scientist with a PhD degree in the field of molecular biology, biochemistry, or cell biology and ideally experienced with retinal biology and diseases

  • You have experience and expertise in the following: cell transduction/transfection with viral and nonviral vectors, immunohistochemistry and confocal microscopy, protein assays such as ELISA and quantitative western, in vitro maintenance and characterization of ocular cell monocultures, retinal organoids, and retinal explants

  • You have very good interpersonal and communication skills, are able to build good working relationships and are an outstanding teammate. Your experience and investigative attitude allow you to work independently, to design, perform, and interpret experiments, and to embark on new scientific methodologies

  • You have been actively engaged in scientific research continuously since his/her PhD (or MD/PhD) and ready to start an RPF postdoctoral activity no later than 4 years after PhD (or MD/PhD)


Important to know:

  • In case the first review of your application was successful, we are going to invite you to an Online Assessment in December

  • The start date of this fellowship is February 1, 2021. Please clearly indicate your preferred starting date on your motivation letter

  • All applications always need to include a CV, motivation letter, a publication list, summary of methods applied, and if available, your PhD certificate


Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

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Tags: RPF 

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Research & Development, Research & Development > Research