PhD in Oncology Discovery Pharmacology Group (3 years)

Switzerland, Zurich, Zurich

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At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. We believe in the urgency of delivering medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision-making and taking action. We believe that good business means a better world. That is why we come to work every single day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The position

Oncology Discovery Pharmacology translates scientific discoveries into effective medicines for cancer patients. The Oncology Discovery Pharmacology Group is an integral unit within pRED Oncology that leads the preclinical assessment of novel drugs candidate, by using state-of-the-art animal facility, innovative preclinical mouse tumor models, along with innovative multiplex technologies and cutting edge preclinical imaging approaches.

Within this environment, we are looking for a talented and motivated graduate student who will bring his/her scientific creativity and natural curiosity to tackle important unmet medical needs.

As PhD student in the Oncology Discovery Pharmacology Group you will focus on exploratory research project titled: “Tumor-Immune co-evolution and therapeutic response in next generation Colorectal Cancer (CRC) mouse models”.

In this PhD project, you will:

• Characterize the immune landscape at different stages of tumor progression on primary and metastatic sites

• Determine the therapeutic efficacy of cancer immunotherapies at different progression stage (early stage vs late stage and primary tumor vs metastases)

• Identify potential signatures responsible for Response vs Resistance to cancer immunotherapies

Who You Are

You are someone who wants to influence your own development. You are looking for a company, which gives you the opportunity to pursue your interests and develop your research skills across different functions. Working in a multicultural environment motivates you. Moreover, you have very good interpersonal and communication skills, you are able to build good working relationships, and are an outstanding team player.

You are/have:

• A Master degree in the field of tumor biology, and/or Immunology.

• Hands-on experience in rodent models of cancer with knowledge and experience in animal handling, anesthetic and surgical procedures

• Have a LTK 1 certificate or equivalent

• Hands-on experience in cell culture techniques and a strong interest in cellular and molecular biology

• The experience and investigative attitude that allows you to work independently, to design, perform, and interpret experiments, and to embark on new scientific methodologies

• Strong presentation skills to communicate scientific data through internal seminars and team meetings, external conferences and research journals

• Fluent in spoken and written English

Application needs to include a CV, two references and a motivation letter.

The graduate student will be enrolled in an academic doctoral external program at an accredited university, selected based on research excellence and international reputation.  During the doctoral research period, a pair of co-supervisors, one based at Roche and the other based at the selected University will mentor the student.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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Roche is an equal opportunity employer.

Vocational & Development Programs, Vocational & Development Programs > Internship