Laboratory Head in Process Chemistry & Catalysis (Evergreen Position)

Switzerland, Basel-City, Basel

de fr es ru tr it pt zh ja

Laboratory Head  Process Chemistry & Catalysis (Evergreen Position​)

At Roche, we believe it is urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

As a Laboratory Head in Process Chemistry you will be working in the department “Process Chemistry & Catalysis” within “Small Molecules Technical Development”.

Behind every presentation of each product sold by Roche is the involvement of Pharma Global Technical Operations (PT). Starting with Phase I of the development process and continuing through to product maturity, PT makes medicines at sites around the world and includes more than 10 000 employees worldwide.

"Global Technical Development" (PTD) is an organization of over two thousand people globally that are integral for the mission of Roche to develop meaningful medicines for patients. Therefore, PTD actively collaborates and develops creative technical solutions to bridge early-stage, late-stage, and commercial product needs. The mandate of the group is, to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, collaboration, dedication, and mutual respect and contributes every single day, continuously improving what it does.

“Small Molecules Technical Development” (PTDC) brings a broad range of experience across drug substance (DS), drug product (DP), analytical sciences and manufacturing S&T, and collaborates closely with key partners in the departments Research and Early Development (pRED / gRED), commercial manufacturing (PTC) and PTD. PTDC is responsible for late stage technical development of our small molecules pipeline, manufacture of DS and DP for clinical studies and Manufacturing Science and Technology (MSAT) across our small molecules manufacturing network.

As a Laboratory Head in Process Chemistry, you will lead a process chemistry lab with 2 to 4 associates responsible for synthesis design and Process Research & Development of small molecules from entry into human through transfer to commercial manufacturing.

Key responsibilities are:

  • Responsibility for a process chemistry laboratory including direct leadership of 2-4 team members

  • Development of chemical processes suitable for manufacturing pharmaceutical active substances in consistent and high quality. The processes will be scalable and robust and cover all aspects of SHE, quality and cost efficiency

  • As a chemical project leader, you will be coordinating all activities within Technical Development to guarantee the timely supply of high quality drug substance

  • Working within an interdisciplinary team of synthetic, analytical and production chemists as well as process safety experts and engineers

  • Interaction with our partners from technical regulatory, quality assurance and formulation development in an international environment

  • Transfer of new development projects from research, for the subsequent process development for clinical supplies – and, ultimately, for the successful transfer of robust manufacturing processes to commercial production

  • Establish and foster good communication with all partners in the areas of quality assurance, regulatory, and commercial manufacturing

  • Preparation and review of scientific documentation for regulatory submissions

What you bring:

  • PhD degree in organic chemistry complemented with post-doctoral experience

  • Publications in scientific literature 

  • Real passion for scientific and technical innovation

  • Excellent interpersonal, communication and coordination skills

  • Initial experience as a people leader 

  • Experience in process research & development and scale-up of small molecules would be an advantage

  • Knowledge in data science would be an advantage

  • Proficient in English, knowledge of German is an advantage

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a range of backgrounds, perspectives, and skills.

If you have questions then please check our FAQs and videos on

You are applying to be part of the Roche Talent Pool. Currently we do not have a vacant role however we are building a pipeline for future opportunities and therefore we are very interested to get in touch with you." 

Roche is an equal opportunity employer.

Research & Development, Research & Development > Research