Principal Data Management Architect, Personalized Healthcare IT (PHC-IT)

United States of America, California, South San Francisco
Switzerland, Basel-City, Basel

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The power of data at scale has transformed almost every industry, personalizing experiences in many aspects of our lives. Yet in healthcare we’ve only scratched the surface. At Genentech and Roche we are accelerating the use of data insights and digital technologies to make significant strides to reach the full potential of personalized healthcare. We are seeking mission-driven, ardent, self-starting, creative individuals to join us in this effort.  

The Principal Data Management Architect will work closely with key stakeholders in the PHC Center of Excellence  and serve as trusted IT strategist to coordinate data management technology strategy with the PHC COE strategy and portfolio. Responsible for driving the development of an IT strategic plan and works with senior stakeholders to identify technologies which enables the business to achieve its PHC 2.0 vision and strategy. The goals is to architect the PHC Global Data Management Platform for Roche/Genentech’s current and future PHC data management needs. The PHC Global Data Management Platform will manage large scale Global Scientific Datasets including Omics, Imaging, Digital, EHR modalities. The Principal Data Management Architect Provides the business stakeholders a window to key innovative technology trends and evolution of technology within the healthcare  industry, which has the potential to accelerate the fulfillment of the strategic vision. Through use of dashboards and governance boards, provides continuing communication to provide the business an overview of the progress of current IT innovation(s).

We expect the Principal Data Management Architect to be a passionate business and product advocate within IT, with proven analytical capabilities. The Principal Data Management Architect must be an effective negotiator, leader and communicator in working with Roche/Genentech’s multiple business units as well as with internal IT cross-functional teams. The ideal candidate will be a self-starter with a passion for transforming healthcare, a high level of flexibility, and commitment. The Principal Data Management Architect will join our diverse community of smart, fun, wholehearted, and engaged informatics professionals from various functional areas. This person will share our community values of passion, courage, integrity, and gratitude -- all in service of our mission, “doing now what patients need next.”


As Principal Data Management Architect on the PHC Pharma IT/Technology team, you will:

  • Partner closely with key stakeholders from PHC Center of Excellence, Research and Early Development teams (REDs), Product Development (PD) and Commercial business groups, and corresponding Pharma IT Groups and Global Infrastructure and Solutions (GIS)

  • Influence senior leaders across Roche and communicate PHC Principal Data Management Architecture and detailed designs IT/Technology vision, strategy, goals, status, and impact.

  • Develops the technology strategy, architecture, and critical investment plan in strategic technologies.

  • Ensures that the technology architecture, solution architecture and detailed designs remain current with the business goals, and directs the development of architecture activities and projects, while aligning with current and long-term business and technology goals.

  • Architect, design and automate large scale data ingestion containing Imaging, Digital, EMR/EHR and Omics from different sources around the globe.

  • Assist in the development of a big data platform in Hadoop using pipeline technologies such as Spark, Oozie, and more to support a variety of requirements and applications

  • Understands the organizational direction, goals and industry competitive environment to determine how architecture can add value to the organization and to business. Makes expert recommendations and decisions clearly linked to the organization's strategy and financial goals.

  • Highlights short-term trade-offs vs long-term commitments and where those are worth implementing or not. Ensures that the Solutions are scalable (technology), efficient (process), effective (cost), and supportable

  • Mentor technical leads/software engineers to enable the individuals and the organization to develop a scalable and stable solution landscape

  • Have a broad knowledge and leverage the technical capabilities of the internal teams and external technology providers and vendors.

  • Conduct market assessments and to identify new capabilities for existing and future business needs.

  • Collaborate with other Strategy and Architecture groups across Roche


  • Bachelor’s degree in Biology, Computer Science, Mathematics, Electrical Engineering, Information Systems or related field; Master/PHD in Business, Mathematics, Science, or Computer Science preferred

  • Overall 10+ years experience in Product delivery and/or architecture, of which at least 5-10 years as a Data Management Architect.

  • Strong Experience in designing and implementing high available and high scalable big data systems; 3+ years of experience in leading implementation of high scalable data management systems required

  • Experience in designing and implementing multi-tenant cloud platforms that rely on large scale datasets.

  • Partner with product and science leads to understand business requirements, and design detailed solutions architecture that meet them.

  • Experience in database, application development, RESTful APIs, Agile development, Full-stack web development, creating and maintaining CI/CD pipelines.

  • Experience architecting and designing data warehouses on a terabyte/petabyte scale including massively parallel processing & columnar databases..

  • Experience with common JavaScript libraries and data visualization.

  • Hand-on experience in Architecting and designing Data Lake in AWS, with potential to grow across different cloud providers i.e. GCP and Azure

  • Deep experience with ingestion and processing of large Genomic, Digital, EMR, EHR, Omics, Imaging data sets coming from different data sources

  • Experience across multiple big data platforms, ETL, data modeling, and business intelligence big data architectures.

  • Experience with the Hadoop ecosystem (Map Reduce, Spark, Oozie, Impala, HBase, etc.) and big data ecosystems (Kafka, Cassandra, etc.) with experience in atleast one of the  SQL language.

  • Hands-on experience in designing and building data solutions in AWS, e.g. S3, EC2, Aurora, Glue, Lambda.

  • Strong Experience in HL7/FHIR data standards, HIPAA, PHI, ISO, GDPR and other global healthcare compliance/regulatory requirements.

  • Proven ability to upwardly influence the strategic direction of business solutions.

  • Ability to work in environment of competing and alternating priorities with constant focus on delivery.

  • Proven ability to balance business demands and fulfillment in terms of standardization, reducing risk and increasing flexibility.

  • Proven ability to relate and adapt vision and strategy to the external environment that affects the organization in terms of economic climate, customer market demand, regulation and other legalities, geography, culture, technology.

  • Excellent communication (written and oral) and presentation skills; solid business acumen; well-honed influencing skills are essential.

  • Self-motivated and team-oriented; able to work both autonomously and effectively as part of a geographically dispersed team

  • Ability to travel up to 25% time