Investor Update

Basel, 11 June 2009

Reminder: Invitation to Roche Accounting Teleconference

We are pleased to invite you to an accounting conference call followed by Q&A on the impact of the Genentech transaction on the Roche Group’s consolidated equity. As previously announced, this call will focus on prime accounting implications in order to provide an appropriate baseline for analyst models.

The call will take place on Friday, June 12th 2009 starting at 14.00 pm CET.

The presentation slides will be available for download from the Roche internet from 07.00 am CET on June the 12th 2009 via the Roche Internet site: http://ir.roche.com

Friday, June 12th, 2009
14.00 pm to 15.00 pm CET
13.00 pm to 14.00 pm BST
08.00 am to 09.00 am EDT

Phone conference call

The live conference call can be accessed using the following dial-in numbers:

+41 (0) 91 610 5600 (EU and RoW)
+44 (0) 207 107 0611 (UK)
+1 (1) 866 291 4166 (USA, toll-free)
Please dial in to the conference call 10 – 15 minutes before the call is scheduled to start.

Participants
Ian Bishop, Head of External Reporting
Dr. Karl Mahler, Head of Investor Relations

A replay of the conference call will be available one hour after the conference call and then for 48 hours. The replay can be accessed using the following dial-in numbers:

+41 (0) 91 612 4330 (EU and RoW)
+44 (0) 207 108 6233 (UK)
+1 (1) 866 416 2558 (USA)

For the replay, listeners will be asked to enter the ID 18095 followed by the # sign.