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Investor Update

Basel, 10 September 2007

R7128 Demonstrates Safety and Potent Antiviral Activity in HCV-Infected Patients

Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers

Dear Investor,
Please find attached two Pharmasset news releases sent out today.

Please do not hesitate to contact us if you have any further questions.