Investor Update

Basel, 18 July 2007

Reminder: Roche's Half Year Results for 2007
19 July - Presentation in London – 14.00 GMT - 15.00 CET - 9.00 AM EST

Roche will publish its Half Year Results for 2007 prior to the opening of the Swiss Stock Exchange on July 19 at 6.00 GMT / 7.00 CET / 1.00 AM EST. Concurrently, the Half Year Presentation Slides and the Half Year Report will be available from the Roche website http://ir.roche.com.
We would like to invite all interested parties to dial in or participate in the event outlined below:

July 19, 2007
The Half Year Presentation followed by Q&A and additional break-out sessions will be held at the Queen Elizabeth Conference Centre, Broad Sanctuary, Westminster, London SW1P 3EE starting from 14.00 GMT / 15.00 CET / 9.00 AM EST. Participants will be:

Franz B. Humer, Chairman of the Board of Directors and Chief Executive Officer
Erich Hunziker, CFO and Deputy Head of the Corporate Executive Committee
William M. Burns, CEO Division Roche Pharma
Severin Schwan, CEO Division Roche Diagnostics

This presentation can be followed by a live audio webcast with synchronized presentation slides accessed via http://ir.roche.com.

Alternatively, you can dial in to the conference using the following dial-in numbers (listen only mode, no live access to speakers):
+41 91 610 56 00 (Europe and ROW)   or
+44 207 107 06 11 (UK)  or
+1 866 291 41 66  (USA)

At 15.50 GMT / 16.50 CET / 10.50 AM EST  the break-out sessions covering the topics Strategy & Finance, Pharmaceuticals, Diagnostics and Accounting will be held following the main Q&A session.

The break-out sessions will be recorded and placed on the Roche website as soon as possible after the event.

REPLAY
A replay will be available one hour after the respective event, for 48 hours. Access is by dialing:
+41 91 612 43 30  (Europe) or +44 207 108 62 33 (UK) or +1 866 416 25 58 (USA) and enter the conference ID 326 followed by the # sign.

The webcast will be available on demand at http://ir.roche.com.