Investor Update

Basel, 16 October 2006

Reminder: Roche’s Third Quarter Sales 2006 Release

Tuesday, 17th October, 2006

Roche will publish its Sales Results for the  3rd Quarter of 2006 prior to the opening of the Swiss Stock Exchange on Tuesday, 17th October, 2006

6.30 CET  /  5.30 GMT  /  0.30 am EDT
Release will be e-mailed and posted on the Roche IR website.
Presentation slides will be posted on the Roche IR website http://ir.roche.com.

14.00 - 15.30 CET  /  13.00 - 14.30 GMT  /  8.00 - 9.30 am EDT
Conference call will start with presentations by senior management followed by a Q&A session (live access to the speakers). Participants will be:

Erich Hunziker, Deputy Head of the Corporate Executive Committee and CFO
William M. Burns, CEO Division Roche Pharma
Severin Schwan, CEO Division Roche Diagnostics

Dial in to the conference 10-15 min prior to the scheduled start using the following numbers:
 +41 (0) 91 610 56 00 (Europe and ROW)
+1 (1) 866 291 41 66 (USA Toll Free)
+44 (0) 207 107 06 11 (UK)

Alternatively a live audio webcast can be accessed via http://ir.roche.com.


A replay of the conference call will be available one hour after the conference call, for 48 hours. Access is by dialing:
+41 91 612 43 30 (Europe and ROW) or
+44 207 108 62 33 (UK)
+1 (1) 866 416 25 58 (USA)
and will be asked to enter the ID 500 followed by the # sign

A replay of the webcast will be available on demand at http://ir.roche.com.