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Investor Update

Basel, 28 August 2006

Genentech and Biogene Idec announced positive results from a phase II trial of Rituxan in relapsing-remitting multiple sclerosis


Dear Investor,
Please find attached a Genentech news release announcing that a Phase II study of Rituxan (Rituximab) for relapsing-remitting multiple sclerosis (RRMS) met its primary endpoint.

Please do not hesitate to contact us if you have any further questions.