Investor Update

Basel, 9 November 2005

Media Briefing - Pandemic influenza and Tamiflu production

Dear Investor,

Today, the Roche Group Media Office will host a media briefing “Pandemic influenza and Tamiflu production”, which may be of interest to you. The briefing will take place at Roche's headquarters in Basel at 10.30 CET.

This presentation can be followed by a live audio webcast accessed via Internet along with presentation slides and factsheets.
A short video of the production and a replay of the webcast will be available from 13.00 CET.

Please do not hesitate to contact us if you have any further questions.