Bond information

Credit Rating of Roche Holding Ltd
	Moody's	Standard & Poor's
Short term	P-1	A-1+
Long term	A1	AA
Outlook	Stable	Stable

Information about Roche's current bonds and notes

This is not an offer of Securities for sale. The Bonds and Notes have not been registered under the U.S. Securities Act of 1933, as amended (the “Securities Act”). The Bonds and Notes may not be offered or sold in the United States or to U.S. persons (as defined in Regulation S) except in transactions exempt from, or not subject to, the registration requirements of the Securities Act.

Roche Finance Europe B.V. (The Netherlands) guaranteed by Roche Holding Ltd (Switzerland)

EMTN Programme (2003); listed in Luxembourg
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
GBP	5.375%	250	200	29 Aug 03	29 Aug 23	XS0175478873

EMTN Programme (2012); listed in Luxembourg
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
EUR	2.0%	1'000	1'000	23 Mar 12	25 Jun 18	XS0760139773

Roche Kapitalmarkt AG (Switzerland) guaranteed by Roche Holding Ltd (Switzerland)

Swiss issuer: 35% withholding tax on coupon payments
Standalone Swiss documentation; listed at SIX (Switzerland)
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
CHF	4.5%	1'500	1'500	23 Mar 09	23 Mar 17	CH0039139263
CHF	3m CHF LIBOR + 20bps	400	400	23 Mar 12	23 Sep 13	CH0180513035
CHF	1.0%	600	600	23 Mar 12	21 Sep 18	CH0180513068
CHF	1.625%	500	500	23 Mar 12	23 Sep 22	CH0180513183

Roche Holdings, Inc. (USA) guaranteed by Roche Holding Ltd (Switzerland)

EMTN Programme (2008); listed in Luxembourg
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
GBP	5.5%	1'250	900	4 Mar 09	4 Mar 15	XS0415625283
EUR	5.625%	2'750	2'100	4 Mar 09	4 Mar 16	XS0415624120
EUR	6.5%	1'750	1'750	4 Mar 09	4 Mar 21	XS0415624716

144a / RegS US documentation; not listed
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
USD	6.0% s.a.	4'500	4'500	25 Feb 09	1 Mar 19	USU75000AM82
USD	7.0% s.a.	2'500	2'500	25 Feb 09	1 Mar 39	USU75000AN65

Genentech, Inc.

US documentation, not listed
Currency	Coupon	Issued Amount (m)	Outstanding Amount (m)	Issue Date	Maturity	ISIN
USD	4.75% s.a.	1'000	1'000	13 Jul 05	15 Jul 15	US368710AG46
USD	5.25% s.a.	500	500	13 Jul 05	15 Jul 35	US368710AC32