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1920 - 1952

History
1920 - 1952: Milestones in Drug Therapy
 
Over a period of 32 year, Roche saw a steady growth of its international business. Not only was it the time of the first synthesis process for vitamin C, by 1938 vitamins were the company's mainstay, and Roche had joined the ranks of the world's leading vitamin producers.

Corporate growth took place in Europe, North and South America and the Far East, creating an ever larger trading and production network upon which Roche would built its presence around the globe.



Era of Emil Barell
1921
Product introduction: Allonal, analgesic sedative and hypnotic
Allonal, an analgesic sedative and hypnotic as a first product using compounds produced by synthetic chemistry, is introduced.
1925
Subsidiary in Tokyo (Japan)
1928
New US plant founded in Nutley
As the New York offices are too small, a new plant is designed – and found – in Nutley to manufacture a wide range of products. The move to Nutley takes place in 1929 and the list of products manufactured locally soon includes barbiturates, specifically Allonal, a hypnotic and sedative that is extremely successful in the United States.
1928 - 31
Introduction of non-voting and voting shares (Genuss-Schein, Inhaberaktie)
From 1928 to 1931 Roche’s share capital was reduced from 8 million to 16’000 Swiss francs in a series of repayments to shareholders. During the same period a stock split doubled the number of bearer shares to 16’000, and a total of 48’000 non-voting equity securities in bearer form were issued.
1933
Industrial synthesis of Vitamin C
Tadeusz Reichstein (Nobel Prize winner 1950) offers Roche a workable method of synthesising vitamin C. When vitamin C proves a commercial success, the process for full production is scaled up.
1933
Product introduction: Saridon, analgesic drug
An effective pain reliever (analgesic), Saridon originally contains phenacetin and is marketed with big success. Saridon is still sold today.
1934
Product introduction: Redoxon, vitamin C preparation
The first 50 kilograms of vitamin C are produced. This marks the real start of vitamin manufacturing at Roche. As a first vitamin preparation, Redoxon is launched.
1938 - 47
Industrial synthesis of Vitamin A, Vitamin B group, Vitamin E, Vitamin K
Roche becomes the leading supplier of vitamins, having mastered the industrial synthesis of vitamin A, B1, B2, E and K1. By 1938 vitamins were the company’s mainstay, encompassing Benerva (vitamin B1), Nestrovit (multi-vitamin), Beflavin (vitamin B2), Ephynal (vitamin E).
1944
Product introduction: Bepanthen, skin care product
Bepanthen, a therapeutic skin care product, is launched in tablet, ampoule and ointment presentations. The active ingredient, dexpanthenol, is converted in the body to pantothenic acid, a member of the vitamin B complex.
1952
Product introduction: Rimifon, antituberculosis drug
Isoniazid, a treatment for tuberculosis, is launched world-wide as Rimifon, helping to eradicate tuberculosis. In the years to follow, Roche will be regarded as a leader in antimicrobial chemotherapy.


1953 - 1965
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