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Investor Update

Basel 19 October 2009

Genentech and Biogen Idec Receive a Complete Response from FDA for Earlier Use of Rituxan for Rheumatoid Arthritis

Dear Investor,
Please find attached a press release issued by Genentech and Biogen Idec in the US with respect to the approval of Rituxan in early and late stage rheumatoid arthritis in the US.

See attached press release