System Engineer I, Sequencing

United States, California, Pleasanton

The System Engineer I at Roche Sequencing Solutions will be part of the system development team focusing on the development of a cutting edge next-generation sequencing (NGS) system for IVD assays and applications. The individual will be part of a team tasked with the design and development of a sample preparation automation solution for the NGS platform.


Experience and Responsibilities:

  • Expertise in IVD instrument design and development is essential, particularly in the area of sample preparation automation for molecular diagnostics testing.
  • Programming skills for industrial liquid handling robots is highly desirable.
  • Nucleic acid based diagnostics technology background and next-generation sequencing experience are highly desirable.
  • Computer engineering skills are a plus.
  • Knowledge of all phases of NGS workflows and data analysis is desirable. Experience with NGS systems development is a plus.


The individual responsibilities are:

  • Programs methods for sample prep workflows on liquid handling robots
  • Works under general supervision, to conduct and monitor laboratory experiments utilizing established and published procedures
  • Writes test cases and implements and executes tests to verify the software and system performance
  • Works closely with external and internal design teams to understand and resolve product performance issues
  • Troubleshoots systems errors and provides root causes of complex HW-SW interaction problems
  • Identifies and communicates opportunities for quality improvements
  • Familiarizes her/himself with new technologies
  • Summarizes experimental results, and reviews conclusions with supervisor/project leader
  • Communicates results of experiments in the form of reports and presentations
  • Performs work according to established internal safety guidelines and procedures, and as specified by appropriate external regulatory agencies (e.g. OSHA)
  • Works independently with general management direction. Work is reviewed in detail over a specific time frame.