System Engineer I, Sequencing

United States, California, Pleasanton

The System Engineer I at Roche Sequencing Solutions will be part of the system development team focusing on the development of a cutting edge next-generation sequencing (NGS) system for IVD assays and applications. The individual will be part of a team tasked with the design and development of a sample preparation automation solution for the NGS platform.


Experience and Responsibilities:

  • Expertise in IVD instrument design and development is essential, particularly in the area of sample preparation automation for molecular diagnostics testing.
  • Nucleic acid based diagnostics technology background and next-generation sequencing experience are highly desirable.
  • Knowledge of all phases of NGS workflows and data analysis is desirable. Experience with NGS systems development is a plus.


The individual responsibilities are: 

  • Works under general supervision, to conduct and monitor laboratory experiments utilizing established and published procedures, and technical and theoretical understanding.
  • Hands-on with a strong instrument/platform development background, the candidate will be asked to troubleshoot systems, identify opportunities for quality improvements, provide root causes of complex HW-SW interaction problems, and communicate test results and corrective recommendations to the team.
  • Summarizes experimental results, and reviews conclusions with supervisor/project leader
  • Communicates results of experiments in the form of reports and presentations
  • Keeps supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas.
  • Performs work according to established internal safety guidelines and procedures, and as specified by appropriate external regulatory agencies (e.g. OSHA)
  • Assesses results for applicability, validity, and conformance to Product Requirements
  • Works independently with general management direction. Work is reviewed in detail over a specific time frame.
  • Writes test cases, and implements and executes automated tests to verify the hardware, software and system performance.
  • He or she will work closely with external and internal design teams to understand and resolve product performance issues.