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ADR Information

Roche’s ADR (American Depositary Receipt) is listed on OTCQX International Premier under the symbol RHHBY. Traded in U.S. Dollars, one (1) Roche ADR represents one quarter (¼) of one underlying non-voting equity security (Genussschein, abbreviated NES). Roche’s non-voting equity security and the Roche voting share are both listed on SIX Swiss Exchange.

SymbolSecurityNo. of securitiesListing/TradingCUSIP/ISIN
RHHBYU.S. security (ADR)Note a)OTCQX771195104
ROGNon-voting equity security (NES)702,562,700SIX Swiss ExchangeCH0012032048
ROVoting share160,000,000SIX Swiss ExchangeCH0012032113

Note a)  The number of ADRs in issue varies depending on demand and conversion in and out of the underlying non-voting equity security (NES).

The Roche ADR facility was initiated in 1992 when one ADR represented one hundredth (1/100) of one non-voting equity security. The current ADR ratio is a result of several splits and ratio changes.

ADR splits and ratio changes
Record dateEffective dateADR splitADR to NES ratio
05 Jan 200909 Jan 20092 for 11 to ¼
21 Jan 200525 Jan 20052 for 11 to ½
Note b)04 May 20011 for 11 to 1
Prior to 04 May 2001--1 to 1/100

Note b) On 3 April 2001, the Board of Directors approved a 100 for 1 split of the non-voting equity security. This was followed by an opposite 1 for 100 change in the ADR to NES ratio. As a result, no new ADRs were distributed.

ADR 5-year dividend history
Declared dateRecord datePay date for ADRGross dividend ($)Net dividend ($) Note c)
06 Mar 200913 Mar 200928 Apr 20091.054140.88045
21 Feb 200806 Mar 200821 Apr 20081.125960.94531
23 Feb 200707 Mar 200720 Apr 20070.690350.57680
09 Feb 200601 Mar 200617 Apr 20060.477060.39375
17 Feb 200502 Mar 200515 Apr 20050.418600.34580

Note c) Dividends are subject to Swiss withholding tax of 35% at the time of initial payment. For ADR holders, the depositary bank performs a tax reclaim process with the Swiss tax authorities. The actual dividend tax paid depends on the specific tax status of the dividend recipient. For the amount listed in the net dividend column, a 15% tax rate has been assumed plus a dividend, reclaim and payment fee of $0.0235 per ADR. The tax reclaim process causes a difference in timing between the record date and the ADR pay date. Roche is considered a qualified foreign corporation for U.S. tax purposes. For further tax questions, please consult a tax advisor.

Other relevant information

In 2006, to facilitate expanded market access and secondary trading, the Roche ADR obtained a securities manual listing by Standard & Poor’s Standard Corporation Records.

Information about buying and selling the Roche ADR as well as information about dividend payments should be addressed to your bank or broker.

ADR depositary bank

J.P. Morgan Chase sponsors and administers the Roche ADR facility. The J.P. Morgan ADR shareholder services can be contacted as follows:

Toll free number: 1 800 990 1135
Hearing impaired: 1 866 700 1652
Outside the U.S.: +1 651 453 2128
Email: jpmorgan.adr@wellsfargo.com

Regular correspondence:
JPMorgan Chase & Co.
P.O. Box 64504
St. Paul, MN 55164-0504
USA

Delivery of ADR certificates and overnight mail:
JPMorgan Chase & Co.
161 N Concord Exchange
South St. Paul, MN 55075

Investor Relations North America

Questions about Roche, its business and products should be addressed to Investor Relations North America:

+1 973 562 2233
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Information accessed herein may not under any circumstances be used for the purpose of, or in connection with, the quotation of any securities on an automated inter-dealer quotation system within the meaning of Rule 12g3-2(b) under the Securities Exchange Act of 1934.