Starting with A for "ACE inhibitor" and continuing through to Y for "Yolk Sac Tumour", we give you succinct explanations for scientific and medical terms in clear and simple words.
- VaricosisExtended formation of so-called varicose veins, particularly in the legs.
1. Primary varicosis with tendency to thrombosis, particularly when blood circulation is slow, e.g. after extended bed rest. Causes: mostly constitutional, as a result of general weakness in connective tissue, which is more frequently manifested with increasing age. Predisposing factors include work in standing, overweight and pregnancy. 2. Secondary varicosis as a consequence of vein disease, which leads to occlusion or local failure of the valves in the affected veins. When there is valve failure in the deeper leg veins there is increased venous reflux through the superficial veins which are connected with the deep leg veins. This is in the opposite direction from normal circulation and is mostly due to the so-called muscle pump.
Mechanical obstacles to venous reflux and the resulting increase in peripheral venous pressure result in the formation of superficial and deep varicose veins, with symptoms of congestion. Combinations of primary and secondary varicosis often occur in the clinic.
Glossary entries: Roche and Walter de Gruyter, Berlin