Central Nervous System

Central nervous system disorders are among the world’s greatest unresolved health problems, and Alzheimer’s disease is one of the biggest threats facing aging industrial societies. There is currently no prospect of a cure for Alzheimer’s, only the possibility of slowing its progression.

Fighting forgetfulness with therapeutic antibodies

Roche is thinking outside the box to attack the disease at its root. We’re researching various strategies for dissolving the brain deposits, known as plaques that are characteristic of Alzheimer’s disease.
One promising approach, identified in collaboration with a partner, is based on a human therapeutic antibody that is custom-designed for this purpose. Patients will benefit because removal of the deposits has been linked to improve cognitive functioning.

New perspectives for schizophrenia patients

Years of research on the central nervous system is leading us in new directions and towards innovative approaches to the treatment of schizophrenia. We have discovered compounds that differ in their mechanism of action from the classical antipsychotics currently used to treat schizophrenia. This may bring fresh hope to patients with psychiatric disorders.